Advanced calcification analysis lectures
This lecture teaches about cancers producing multiple clusters of crushed stone-like, pleomorphic, malignant type calcifications. Correlation of multimodality images with large format histopathologic images reveals cancers that are much more extensive than suggested by the mammographic findings, because non-calcified breast cancer of ductal origin fill most of the same lobe of the breast. Each case concludes with a summary of practical take-home messages.
These carefully chosen, fully worked-up cases cover the full spectrum of malignant-type calcifications seen at mammography. You will learn how to find faint and subtle calcifications and recognize malignancy by the distribution of the calcifications, even when the individual calcifications appear benign. Our multimodality diagnostic approach benefits from the strengths of magnification mammography, ultrasound and MRI. The imaging findings are correlated in every case with large format thin section (and often thick section) histopathology images to show the underlying structure of the malignancies we see at imaging. Every case has illustrated teaching points reviewing the major findings and commenting on the appropriateness of the management. These lectures improve your skills in perception and diagnosis and give you greater confidence when communicating your findings to your pathologists and surgeons.