Extensive high grade carcinoma originating from the major lactiferous ducts.
This lecture deals with the breast cancer subtype that originates from the major lactiferous ducts but it does not have mammographically demonstrable calcifications. The proliferating, cancer filled ducts may be seen on the mammogram as architectural distortion. Perception of this subtype of breast cancer is a real challenge for radiologists. At the time of diagnosis, the disease occupies most of a breast lobe, extending from the nipple to the chest wall.
This lecture explains the imaging and clinical features of this breast cancer subtype and has important implications for management.
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